Myeloid Sarcoma of the Breast of A Young Boy: A Case Report

Huque Mahfuz(1), Mohammad Elias Hossain(2), Mohammed Mosleh Uddin(3), Md Mostafil Karim(4), Md Golam Robbani(5)
(1) , Bangladesh
(2) , Bangladesh
(3) , Bangladesh
(4) , Bangladesh
(5) , Bangladesh

Abstract

Granulocytic sarcoma also called myeloid sarcoma (MS) is an extramedullary tumour of immature granulocytic cells. It is a rare entity and most frequently associated with acute myeloid leukaemia (AML) but can occur with other myeloproliferative disorders. It may occur at any site, leading to very varied clinical presentations. Although it can occur in a number of areas of the body, the involvement of the breast is uncommon. We present a rare case of MS in a 14?year?old boy with a non-tender lump in the left breast that had been apparent for five months. Available diagnostic techniques, including ultrasound and magnetic resonance imaging were systematically performed. After mastectomy, biopsy and immunohistochemistry was done. Immuno-histochemical stains were positive for CD45 (haematological marker) and myeloid markers, such as myeloperoxidase (MPO), and CD68, CD43 suggesting the diagnosis of MS. Although MS is a rare tumour in breast and its diagnosis is usually difficult, the clinician must know about its existence to make differential diagnosis.

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Authors

Huque Mahfuz
dulles1965@gmail.com (Primary Contact)
Mohammad Elias Hossain
Mohammed Mosleh Uddin
Md Mostafil Karim
Md Golam Robbani
Author Biographies

Huque Mahfuz

Colonel, Department of Haematology, Combined Military Hospital (CMH) Dhaka

Mohammad Elias Hossain

Department of Haematology, Combined Military Hospital (CMH) Dhaka

Mohammed Mosleh Uddin

Colonel, Department of Haematology, Combined Military Hospital (CMH), Dhaka

Md Mostafil Karim

Colonel, Department of Haematology, Combined Military Hospital (CMH), Dhaka

Md Golam Robbani

Department of Haematology, Combined Military Hospital (CMH), Dhaka

1.
Mahfuz H, Hossain ME, Uddin MM, Karim MM, Robbani MG. Myeloid Sarcoma of the Breast of A Young Boy: A Case Report. Haematol J Bangladesh [Internet]. 2020 May 13 [cited 2024 May 29];2(2):61-3. Available from: https://journal.hematologybd.org/index.php/haematoljbd/article/view/21

Article Details

How to Cite

1.
Mahfuz H, Hossain ME, Uddin MM, Karim MM, Robbani MG. Myeloid Sarcoma of the Breast of A Young Boy: A Case Report. Haematol J Bangladesh [Internet]. 2020 May 13 [cited 2024 May 29];2(2):61-3. Available from: https://journal.hematologybd.org/index.php/haematoljbd/article/view/21

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